Electrophysiology
Electrophysiology requires slicing of live soft tissues. The quality of your experiment depends on the quality of the tissue slice. Your daily productivity also depends on the quality of the tissue slice. The viability of the brain slice, especially the healthy neurons in the top surface layers are crucial to the success of brain slice patch clamp electrophysiology. The Compresstome™ VF-200 and VF-300 produce the highest quality brain slices for these researches.
Our Products Have Tremendous Advantages:
Doubling the brain slice viability.
The pre-stress force created by the compression counteracts the mechanical stress of the cutting blade which reduces cell damage during slicing, resulting in healthier slices with more viable cells. There are many good neurons on the top surface that can be chosen for experiment. Greatly increases your productivity.
Older animal and more sensitive brain areas.
Vulnerable tissues of older animals and more sensitive nuclei of the brain can still be sliced with the Compresstome™ VF-200 and VF-300, greatly expanding the range of experiments that you can do.
Smoother and cleaner cutting surface.
The wavy chatter marks or vibration marks indicate the trails of the oscillating blade of the slicer. In the VF-200 and VF-300 microtome, the vibration mark is dramatically reduced from the slice surface.
High quality images.
Images of slices cut with the Compresstome™ VF-200 and VF-300 are sharper ,with fewer scratches and distortion. As seen from the sample images on the slice album page, more details can be observed in these slices.
Reduce thermal shock.
Slicing can be performed in warm temperature (32 degrees C) as well as 4 degrees C. The ability to slice in warm temperature eliminates drastic temperature fluctuation, reducing thermal shock to the tissues.
Quick recovery.
The ability to slice in warm temperature allows recovery in less than 20 minutes.
Consistent slice thickness.
The unique specimen embedding, holding and clamping mechanisms minimizes specimen movement in all three dimensions during slicing. Consistent slice thickness can be achieved. Slice thickness varies less than 5 percent of the slice thickness (250 µm), compared to 10 to 20 percent in classic slicers.
Minimal moving parts and quiet operation.
Every effort is used to minimize mechanical vibration on the Compresstome™ microtome. This allows them to reduce energy precipitating on the slice.
Versatile.
Need to do some immunohistochemistry work as well? The VF-200 and VF-300 are also great at slicing fixed tissues, saving your money and lab space.
Fast cutting.
For vibrating blade tissue slicers, it takes 10 to 30 seconds to cut a slice. The VF-200 and VF-300 takes less than 5 second to cut a slice.
Simple.
The operation of the VF-200 and VF-300 are simpler than that of other vibrating slicers. Close monitoring is unnecessary. No experience is required to operate the device.
Our Published Papers
Take a look at our published papers on electrophysiology to see the revolution we have brought to the research community.